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Three Hoodia for $29.99African Hoodia Promotes Weight Loss

Hoodia P57

What advocates claim: Scientists believe a compound in hoodia called P57 acts on the hypothalamus (located in the brain), maki9ng your stomach feel that it is already full of food. Many people taking hoodia eat less and lose weight, even without diet and exercise.

What we know: No randomized, long-term studies have been conducted on human subjects to prove the supplement’s safety and effectiveness. In a small, unpublished 2001 study by pharmaceutical companies Phytopharm and Pfizer, nine obese patients taking a high-dose extract of hoodia over 15 days consumed an average of 1,000 fewer calories, significantly fewer than a control group.

Hoodia is derived from a spiny, cucumber-shaped succulent that grows in the Kalahari Desert of southern Africa. Hoodia gordonii has been used for generations by the San bushmen to blunt hunger during long trips across the desert.

Hoodia Featured on 60 Minutes

More recently, hoodia has gained attention as a diet aid. In 2004, 60 Minutes correspondent Lesley Stahl gave the supplement national exposure when she traveled to South Africa. After trying it, she reported she wasn’t hungry for the rest of the day. On the heels of this publicity, hoodia is everywhere. Hoodia-based products are available in drug and health food stores and on the Internet. A Google search yields more than 2 million hits.

Yet even if the South African Hoodia plant proves an effective diet aid, supplements may not work the same way. What’s more, products on the market may not actually contain hoodia, which is a slow-growing, endangered shrub that is hard to propagate. No government agency oversees the accuracy of ingredient labeling on dietary supplements.

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